Famed monster slayer Gabriel Van Helsing is dispatched to Transylvania to assist the last of the Valerious bloodline in defeating Count Dracula. Anna Valerious reveals that Dracula has formed an unholy alliance with Dr. Frankenstein's monster and is hell-bent on exacting a centuries-old curse on her family.
For years, Blade has fought against the vampires in the cover of the night. But now, after falling into the crosshairs of the FBI, he is forced out into the daylight, where he is driven to join forces with a clan of human vampire hunters he never knew existed—The Nightstalkers. Together with Abigail and Hannibal, two deftly trained Nightstalkers, Blade follows a trail of blood to the ancient creature that is also hunting him—the original vampire, Dracula.
In the millenium version of this classic Gothic horror we find Abraham Van Helsing, who has tangled with Count Dracula in the past, working as an English antiques dealer. Simon is a vampire hunter in training under his apprenticeship.
Vlad Tepes is a great hero, but when he learns the Sultan is preparing for battle and needs to form an army of 1,000 boys, he vows to find a way to protect his family. Vlad turns to dark forces in order to get the power to destroy his enemies and agrees to go from hero to monster as he's turned into the mythological vampire, Dracula.
The church enlists a team of vampire-hunters to hunt down and destroy a group of vampires searching for an ancient relic that will allow them to exist in sunlight.
Jonathan Harker, a real state agent, goes to Transylvania to visit the mysterious Count Dracula and formalize the purchase of a property in Wismar. Once Jonathan is caught under his evil spell, Dracula travels to Wismar where he meets the beautiful Lucy, Jonathan's wife, while a plague spreads through the town, now ruled by death.
When Dracula leaves the captive Jonathan Harker and Transylvania for London in search of Mina Harker—the reincarnation of Dracula's long-dead wife, Elisabeta—obsessed vampire hunter, Dr. Van Helsing sets out to end the madness.
Bella once again finds herself surrounded by danger as Seattle is ravaged by a string of mysterious killings and a malicious vampire continues her quest for revenge. In the midst of it all, she is forced to choose between her love for Edward and her friendship with Jacob, knowing that her decision has the potential to ignite the ageless struggle between vampire and werewolf. With her graduation quickly approaching, Bella is confronted with the most important decision of her life.